Chromosome 16 represents almost 3% of the total DNA in cells.
|Summary:||Gene examples of chromosome 16:|
|The MEFV (Mediterranean fever) gene encodes the protein pyrin. Pyrin is produced in white blood cells and plays a role in inhibiting the inflammatory response after an infection. Familiar Mediterranean fever results from an inherited mutation in the MEFV gene. It is characterized by an inappropriate or prolonged inflammatory response with resulting fever or inflammation in the abdomen, chest, joints or skin.||The MSLN gene encodes a preprotein that is cleaved into two products, megakaryocyte potentiating factor and mesothelin. Mesothelin is a cell surface protein present on mesothelium (a protective lining that covers most of the body's internal organs), mesotheliomas (malignant cells develop in the mesothelium) and ovarian cancers. It may play a role in cellular adhesion.|