Chromosome 2 is the second largest human chromosome. It represents almost 8% of the total DNA in cells.
- large sized chromosome
- about 243,000,000 base pairs
- about 1,888 genes
Gene examples of chromosome 2:
COL3A1, COL4A3, COL4A4, COL5A2: These genes encode different types of collagens. Collagens form a family of proteins that strengthen and support many tissues in the body, including skin, ligaments, bones, tendons, muscles and the extracellular matrix (the space between cells and tissues). Mutations in these genes can cause hyperextensibility and fragility of the skin and joint hypermobility (Ehlers-Danlos syndrome) or damages of kidney, inner ear and eye (Alport syndrome).
The BMPR2 gene belongs to a family (bone morphogenetic protein receptor family) of genes identified for its role in regulating the growth and differentiation of mainly bone and cartilage.
The chromosome 2 image
The whole chromosome 2 image has a width of 3500 px and a height of 69415 px. It is too big to display here but you can download the chromosome 2 image. A 200 px wide overview of the chromosome can be seen on the right (bottom). Additionally, we show some details out of the original sized chromosome picture below.