Chromosome 1

Chromosome 1 is the largest human chromosome. It represents approximately 8% of the total DNA in cells.


  • autosome
  • large sized chromosome
  • about 247,000,000 base pairs
  • 2,782 known genes

Gene examples of chromosome 1:

The PARK7 gene provides instructions for making a protein called DJ-1. The DJ-1 protein has several functions like protecting the cells, particularly brain cells, from oxidative stress or to disarm damaged or unwanted proteins as a chaperone molecule. Mutations in the PARK7 gene cause early-onset Parkinson disease with a loss of dopamine-producing nerve cells as a characteristic feature.

The DIRAS3 gene: The protein encoded by this gene occurs in normal ovarian and breast epithelial cells and appears to be a putative tumor suppressor gene. Mutations in this gene can cause breast and ovarian cancers.

The chromosome 1 image

The whole chromosome 1 image has a width of 3500 px and a height of 70643 px. It is too big to display here but you can download the chromosome 1 image. A 200 px wide overview of the chromosome can be seen on the right (bottom). Additionally, we show some details out of the original sized chromosome picture below.

Image details (examples):

The following cropped picture shows details of chromosome 1. Look at the circle in the middle of the picture and close your eyes just a little bit. Strange structures will occur.

Some repeating patterns of a section in chromosome 1: